Below is the code where you can Filter a row and then update a column value
Dim dv As DataView
dv = New DataView(ds.Tables(0))
dv.RowFilter = "PartNum='" & Me.txtParts.Text & "'"
iCount = dv.Count
If iCount = 1 Then
dv(0)("Qty") = Convert.ToInt32(dv(0)("Qty")) + Convert.ToInt32(Me.txtQty.Text)
gvParts.DataSource = ds
gvParts.DataBind()
iCount = 0
dv = Nothing
Return
End If